Publications on Diabetes | Imperial College London Diabetes Centre

2022

Diabetes and Ramadan: Practical Guidelines 2021.

Hassanein M, Afandi B,… Lessan N… Ali T,… Diabetes and Ramadan: Practical guidelines 2021. Diabetes Res Clin Pract. 2022 Jan 8;185:109185. doi: 10.1016/j.diabres.2021.109185.

Total energy expenditure is repeatable in adults but not associated with short-term changes in body composition.

Rimbach R, Yamada Y,… Lessan N… Nat Commun. 2022 Jan 10;13(1):99. doi: 10.1038/s41467-021-27246-z. PMID: 35013190; PMCID: PMC8748652.

Weight and Glycemic Control Outcomes of Bariatric Surgery and Pharmacotherapy in Patients With Melanocortin-4 Receptor Deficiency.

Fojas E, Saradalekshmi KR, Ali T, Nadler EP, Lessan N. Front Endocrinol (Lausanne). 2022 Jan 13;12:792354. doi: 10.3389/fendo.2021.792354. PMID: 35095762; PMCID: PMC8793826.

Ramadan Fasting is associated with a modest rise in TSH levels in patients with primary hypothyroidism.

Alkaf B, Siddiqui M, Ali T, Bakir A, Murphy K, Meeran K, Lessan N. Thyroid. 2022 Feb 12. doi: 10.1089/thy.2021.0512. Epub ahead of print. PMID: 35152772.

Ramadan Fasting Among Older Children and Adolescents with Type 1 Diabetes Mellitus: A Real-World Study From the UAE.

Muammar T, Fojas E, Helal R, Lessan N. Front. Nutr. 9:786678. doi: 10.3389/fnut.2022.786678

The Effect of Coronavirus Disease-19 Pandemic Lockdown and the Overlapping Ramadan Fasting Period on Glucose Control in Insulin-Treated Patients with Diabetes: A Flash Glucose Monitoring Study.

Helal R, Ashraf T, Majeed M, Lessan N. Front. Nutr. 9:843938. doi: 10.3389/fnut.2022.843938

Fine-Scale Genetic Structure in the United Arab Emirates Reflects Endogamous and Consanguineous Culture, Population History, and Geography.

Katherine S Elliott, Marc Haber, Hinda Daggag, …, Bindu Shobi, Tariq Ghulam, Dalia Haj, Alia Al Tikriti, Alshafi Mohammad, Suma Antony, Maitha Alyileili, Shatha Alaydaroos, …, Houman Ashrafian, Maha T Barakat. Mol Biol Evol. 2022 Mar 2;39(3):msac039. doi: 10.1093/molbev/msac039

Low Detection Rates of Genetic FH in Cohort of Patients With Severe Hypercholesterolemia in the United Arabic Emirates.

Antoine Rimbert, Hinda Daggag, Peter Lansberg, Adam Buckley, Martijn Viel, Roan Kanninga, Lennart Johansson, Robin P F Dullaart, Richard Sinke, Alia Al Tikriti, Jan Albert Kuivenhoven, Maha Taysir Barakat. Front. Genet. 2022 Jan 12:809256 https://doi.org/10.3389/fgene.2021.809256

2021

Bariatric surgery in the treatment of patients with obesity and type 1 diabetes: A retrospective study of clinical data.

Nagi Mohammed, Adam Buckley, Mohgah Elsheikh, Matthew Alum, Sara Suliman, Mohammed Al Hadad, Carel W le Roux, Nader Lessan and Mohamed Suliman. Diabetes Obesity and Metabolism. 2021 Mar. doi: 10.1111/dom.14369

A standard calculation methodology for human doubly labeled water studies.

Speakman JR, Yamada Y, Sagayama H, Berman ESF, Ainslie PN, Andersen LF,…, Lessan N et al. Cell Reports Medicine. 2021 Feb. doi: 10.1016/j.xcrm.2021.100203

Daily Energy Expenditure through the Human Life Course.

Pontzer H, YamadaY , Sagayama H, Ainslie P N, Andersen L F, Anderson L J,…, Lessan N, Speakman J R and the International Atomic Energy Agency Doubly Labeled Water database group Science 373, 808–812 (2021).

Endocrinology in the Time of COVID: a Rapid Evolution of Knowledge and Care.

Rizvi A A, Stoian A P, Lessan N, Rizzo M. Medicina 2021, 57(8), 805.

Physical activity and fat-free mass during growth and in later life.

Westerterp K R, Yamada Y, Sagayama H, Ainslie P N, Andersen L F, Anderson L J,…, Lessan N, …, Speakman J R and the International Atomic Energy Agency Doubly Labeled Water database group. American Journal of Clinical Nutrition 2021. doi: 10.1093/ajcn/nqab260

Promoting a Syndemic Approach for Cardiometabolic Disease Management During COVID-19: The CAPISCO International Expert Panel.

Wael Al Mahmeed1, Khalid Al-Rasadi,… Nader Lessan… Front. Cardiovasc. Med. 8:787761. doi: 10.3389/fcvm.2021.787761

2020

Obesity and Diabetes in an Arab population: Role of Adenovirus 36 Infection.

Nader Lessan, Koramannil Radha Saradalekshmi, Budour Alkaf, Maria Majeed, Maha T Barakat, Zendra P L Lee, Richard Atkinson. Scientific Reports. 2020 May. doi: 10.1038/s41598-020-65008-x

Ramadan fasting in insulin-treated patients is associated with potentially unfavourable changes in glucose metrics: A flash glucose monitoring (FGM) study.

Ilham Saadane, Tomader Ali, Ahmed El-Laboudi, Nader Lessan. Diabetes Research and Clinical Practice. 2020 Dec. doi: 10.1016/j.diabres.2020.108592

Secondary analyses of global datasets: do obesity and physical activity explain variation in diabetes risk across populations?

Budour Alkaf, Alexandra Blakemore, Marjo-Riitta Jarvelin, Nader Lessan. International Journal of Obesity. 2020 Jan. doi: 10.1038/s41366-021-00764-y

2019

Routine clinical use of Liraglutide 3 mg for the treatment of obesity: Outcomes in non-surgical and bariatric surgery patients.

Suliman M, Buckley A, Al Tikriti A, Tan T, le Roux CW, Lessan N, Barakat M. Diabetes Obesity and Metabolism. 2019 May. doi: 10.1111/dom.13672

Parameters of Bone and Cardiovascular Health Related to 25-Hydroxyvitamin D Status in Emirati Nationals attending Primary Care and Diabetes services: a retrospective cohort study.

Adam J Buckley, Maha T Barakat, Michael F Holick and Nader Lessan. Scientific reports. 2019 Mar. doi: 10.1038/s41598-019-40523-8

Energy metabolism and Intermittent Fasting: the Ramadan perspective.

Nader Lessan, Tomader Ali. Nutrients. 2019 May. doi:10.3390/nu11051192

Diabetes and Ramadan: utility of flash-glucose monitoring derived markers of glycaemic control and comparison with glycosylated haemoglobin.

Ilham Saadane, Tanveer Ashraf, Tomader Ali, Nader Lessan. Diabetes Research and Clinical Practice. 2019 May. doi: 10.1016/j.diabres.2019.05.020

Paradoxical Vitamin D Deficiency in a Sunny Country: A Narrative Review of the Literature from the United Arab Emirates (1992–2018)

Salem A. Beshyah, Khadija Hafidh, Dima K. Abdelmannan, Abdul Jabbar, Wafic S. Wafa, Aly B. Khalil. Ibnosina Journal of Medicine and Biomedical Sciences. 2019 Oct. doi: 10.4103/ijmbs.ijmbs_50_19

2018

Indeterminate Thyroid Nodules: A Pragmatic Approach

Khalil AB, Dina R, Meeran K, Bakir AM, Naqvi S, Al Tikritti A, Lessan N, Barakat MT. European Thyroid Journal. 2018 Jan;7(1):39-43. doi: 10.1159/000484600

The effects of Ramadan fasting on activity and energy expenditure.

Lessan N, Saadane I, Alkaf B, Hambly C, Buckley AJ, Finer N, Speakman JR, Barakat MT. American Journal of Clinical Nutrition. 2018 Jan 1;107(1):54-61. doi: 10.1093/ajcn/nqx016

Trimester specific reference ranges for serum TSH and Free T4 among United Arab Emirates pregnant women.

Aly Bernard Khalil, Bashir Taha Salih, Onismos Chinengo, Ma Remy D. Bardies, Andrew Turner, Laila O. Abdel Wareth. Practical Laboratory Medicine. 2018 Apr; doi: 10.1016/j.plabm.2018.e00098

Diabesity in the Arabian Gulf: Challenges and Opportunities

Khalil AB, Beshyah SA, Abdella N, Afandi B, Al-Arouj MM, Al-Awadi F, Benbarka M, Ben Nakhi A, Fiad TM, Al Futaisi A, Hassoun AA, Hussein W, Kaddaha G, Ksseiry I, Al Lamki M, Madani AA, Saber FA, Abdel Aal Z, Morcos B, Saadi H. Oman Medical Journal. 2018 Jul. doi: 10.5001/omj.2018.53

Non-alcoholic fatty liver disease: relationship with cardiovascular risk markers and clinical endpoints.

Buckley A, Louise Thomas E, Lessan N, Trovato FM, Trovato GM, Taylor-Robinson SD. Diabetes Research and Clinical Practice. 2018 Aug. doi: 10.1016/j.diabres.2018.08.011

Efficacy of bariatric surgery in improving metabolic outcomes in patients with diabetes. A 24-month follow-up study from a single center in the UAE.

Hanadi Alnageeb, Elamin Abdelgadir, Azza Khalifa, Mohamed Suliman, Subash Chander Gautam, Laurent Layani, Sriganesh Subramaniam, Alaaeldin Bashier. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 2018 Sep. doi: 10.2147/DMSO.S176761

The epidemiology and economic burden of obesity and related cardiometabolic disorders in the United Arab Emirates: A systematic review and qualitative synthesis.

Radwan H, Ballout R, Hasan H, Lessan N, Karavetian M, Rizk R. Journal of Obesity. 2018 Dec. doi: 10.1155/2018/2185942

SGLT2 Inhibition May Precipitate Euglycemic DKA after Bariatric Surgery.

Hassan Elasha, Ali Mekki Elsheikh, Wafic Wafa, Karim Meeran. Clinical Diabetes and Research. 2018 Jul. 2018, 2(1):40-42

Exploring the Safety of Sodium Glucose Co-Transporter-2 Inhibitors at the Imperial College London Diabetes Centre, UAE.

Raad Nari, Maura Moriaty, Maha T. Barakat. World Academy of Science, Engineering and Technology: International Journal of Medical and Health Sciences. 2018 Dec; Vol:12, No:12, 2018

Central Serous Chorioretinopathy: A Report of Two Unusual Causes.

Imran Ahmed Ansari, Ossama Abdelwahed El Haddad. Egyptian Retina Journal. 2018 Dec. doi:10.4103/erj.erj_11_18

2017

Environmental determinants of previtamin D synthesis in the United Arab Emirates.

Buckley AJ, Hannoun Z, Lessan N, Holick MF, Barakat MT. Dermatoendocrinology. 2017 Feb 6;9(1):e1267079. doi: 10.1080/19381980.2016.1267079

Diabetes and Ramadan: Practical guidelines

Hassanein M, Al-Arouj M, Hamdy O, Bebakar WMW, Jabbar A, Al-Madani A, Hanif W, Lessan N, Basit A, Tayeb K, Omar M, Abdallah K, Al Twaim A, Buyukbese MA, El-Sayed AA, Ben-Nakhi A; International Diabetes Federation (IDF), in collaboration with the Diabetes and Ramadan (DAR) International Alliance. Diabetes Research and Clinical Practice. 2017 Apr;126:303-316. doi: 10.1016/j.diabres.2017.03.003 ISBN 978-2-930229-85-0 EAN: 9782930229850

Management of prolactinomas: a survey of physicians from the Middle East and North Africa.

Beshyah SA, Sherif IH, Chentli F, Hamrahian A, Khalil AB, Raef H, El-Fikki M, Jambart S. Pituitary. 2017 Apr;20(2):231-240. doi: 10.1007/s11102-016-0767-5

2016

Melanocortin-4 receptor signaling is not required for short-term weight loss after sleeve gastrectomy in pediatric patients.

Jelin EB, Daggag H, Speer AL, Hameed N, Lessan N, Barakat M, Nadler EP. International Journal of Obesity (London). 2016 Mar;40(3):550-3. doi: 10.1038/ijo.2015.230

Subclinical Inflammation and Endothelial Dysfunction in Young Patients with Diabetes: A Study from United Arab Emirates.

Aburawi EH, AlKaabi J, Zoubeidi T, Shehab A, Lessan N, Al Essa A, Yasin J, Saadi H, Souid AK. PLoS One. 2016 Jul 26;11(7):e0159808. doi: 10.1371/journal.pone.0159808

2015

Glucose excursions and glycaemic control during Ramadan fasting in diabetic patients: insights from continuous glucose monitoring (CGM).

Lessan N, Hannoun Z, Hasan H, Barakat MT. Diabetes & Metabolism. 2015 Feb;41(1):28-36. doi: 10.1016/j.diabet.2014.11.004

Latent Autoimmune Diabetes in Adults in the United Arab Emirates: Clinical Features and Factors Related to Insulin-Requirement.

Maddaloni E, Lessan N, Al Tikriti A, Buzzetti R, Pozzilli P, Barakat MT. PLoS One. 2015 Aug 7;10(8):e0131837. doi: 10.1371/journal.pone.0131837

Ramadan and diabetes: What we see, learn and understand from continuous glucose monitoring.

Monnier L, El Azrak A, Lessan N, Rochd D, Colette C, Bonnet F. Diabetes & Metabolism. 2015 Dec;41(6):456-62. doi: 10.1016/j.diabet.2015.09.002

2014

Painful swollen thigh in a patient with poorly controlled diabetes.

Elasha HM, Hareez NB, Joboori AS, Teir J, Mubarak ES. Clinical Medicine (London, England). 2014 Jun;14(3):319. doi: 10.7861/clinmedicine.14-3-319

2013

A young man with a dizzy spell and acute abdominal pain.

Elasha HM, Anjum F, Almalki MH. Clinical Medicine (London, England). 2013 Oct;13(5):520-1. doi: 10.7861/clinmedicine.13-5-520

2012

Ramadan fasting: a study of changes in glucose profiles among patients with diabetes using continuous glucose monitoring.

Lessan N, Hasan H, Barakat MT. Diabetes Care. 2012 May;35(5):e37. doi: 10.2337/dc11-2037

2011

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