Conditions We Treat
We specialise in treating a wide range of lipid disorders, including:
- Familial Hypercholesterolemia (FH)
Familial hypercholesterolemia is a genetic disorder that causes very high levels of low-density lipoprotein (LDL) cholesterol, often referred to as "bad cholesterol." This condition runs in families, and without treatment, it can lead to early heart disease or stroke. - Homozygous Familial Hypercholesterolemia (HoFH)
Homozygous familial hypercholesterolemia is a rare and severe form of FH where both parents pass on the gene mutation. This leads to extremely high cholesterol levels, often exceeding 400-600 mg/dL. Without intervention, it can cause heart disease in childhood or adolescence. - Elevated Lipoprotein(a)
Lp(a) (pronounced “lipo–protein little a” or “LP little a”) is a lipoprotein rich in cholesterol.
Lp(a) is a particle that carries cholesterol in the blood just like LDL (bad)cholesterol. High Lp(a) levels are associated with higher risk for heart disease and stroke related to build up of plaque in the arteries, development of blood clots, and inflammation. Lp(a) levels are inherited and and caused by a dominant gene. If you have inherited the gene for elevated Lp(a), each of your siblings and children has a 50% chance of having inherited an elevated Lp(a) too.
This inherited condition often goes undiagnosed until complications arise. - Hypertriglyceridemia
This condition is characterised by abnormally high levels of triglycerides, a type of fat found in the blood. If left untreated, it can lead to pancreatitis, fatty liver disease, and an increased risk of cardiovascular problems. - Mixed Dyslipidemia
Mixed dyslipidemia occurs when a person has high levels of LDL cholesterol and triglycerides, along with low levels of HDL cholesterol. This combination significantly raises the risk of heart disease. - Statin Intolerance
Statins are commonly prescribed to lower cholesterol, but some individuals experience side effects such as muscle pain, liver problems, or digestive issues. At our clinic, we work with patients who cannot tolerate statins to explore alternative therapies, including non-statin medications and cutting-edge treatments like PCSK9 inhibitors and other innovative drugs. - Lipid Management from Pre-conception to Pregnancy through Lactation
Managing elevated low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) before, and during pregnancy and lactation can be challenging. During uncomplicated pregnancies LDL-C levels can increase up to 60%, TG by 200% (but not usually >250 mg/dL). Lifestyle modifications remain a cornerstone of treatment including a heart-healthy eating plan, weight management, and an exercise plan. Our multi-disciplinary team, including a Lipid Specialist, registered dietitian is often helpful in diagnosing and treating dyslipidemia during pregnancy to support maternal-fetal health.